CDR assessment
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Descrizione
In the PreciAb™ platform, key steps of antibody development are described as follow, Antibody structure construction through combining structure- and homology-based modeling methods Structure optimization by dynamics simulation, rotamer library,...
mostra di piùAntibody structure construction through combining structure- and homology-based modeling methods
Structure optimization by dynamics simulation, rotamer library, loop modeling, and etc.
Complementarity-determining region (CDR) identification on the basis of tertiary structure of the antibody
Antibody-antigen complex modeling and interaction analysis
Paratope and epitope identification and key residues analysis
Computer-aided antibody affinity maturation and function modification
Global analysis and optimization of antibody biophysical properties (thermodynamic stability, aggregation propensity, immunogenicity)
https://www.creative-biolabs.com/preciab/preciab-platform.htm
Informazioni
Autore | echo han |
Organizzazione | echo han |
Sito | - |
Tag |
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