Abbott Mysteries was a comedy-mystery radio program adapted from the novels of Frances Crane (1896-1981). Initially a summer replacement for Quick As a Flash, the series was heard on Mutual and NBC between the years 1945 and 1955.

The Mutual series, sponsored by Helbros Watches, debuted June 10, 1945, airing Sundays at 6 p.m. The scripts by Howard Merrill and Ed Adamson were in the lighthearted tradition of Mr. and Mrs. North. Julie Stevens and Charles Webster starred as Jean and Pat Abbott, a San Francisco married couple "who were habitually involved in various sorts of mayhem and in solving murders."

 In the supporting cast were Jean Ellyn, Sydney Slon and Luis van Rooten.Moving to 5:30 p.m.in 1946, Les Tremayne and Alice Reinheart took over the roles until the end of the series on August 31, 1947.Seven years later, the characters returned October 3, 1954, on NBC in The Adventures of the Abbotts, broadcast on NBC Sunday evenings at 8:30 p.m. In this series, the Abbotts were portrayed by Claudia Morgan and Les Damon. The NBC series ran until June 12, 1955.