Alexis Hejna joins Mark Radulich for a TV Party Tonight talking The PowerPuff Girls Season 1! The Powerpuff Girls is an American animated television series created by animator Craig McCracken for Cartoon Network. The show centers on Blossom, Bubbles, and Buttercup, three girls with superpowers, as well as their father, the brainy scientist Professor Utonium, who all live in the fictional city of Townsville, USA. The girls are frequently called upon by the town's childlike and naive mayor to help fight nearby criminals using their powers.