Approximately 20% of the population suffer from chronic pain (Ashar et al., 2021). It is not uncommon for back pain, knee pain, headaches, etc. to have no clear physical cause, even after the most intensive examinations. At the same time, there are people, for example, whose spine shows several herniated discs in magnetic resonance imaging and yet are completely free of symptoms! These and numerous other findings suggest that pain largely originates (and is maintained) in our brain. The new "PAIN REPROCESSING THERAPY" makes use of this knowledge and was able prove itself in a first clinical study...
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Studies (only a small selection):

Ashar, Y. K., Gordon, A., Schubiner, H., Uipi, C., Knight, K., Anderson, Z., ... & Wager, T. D. (2021). Effect of pain reprocessing therapy vs placebo and usual care for patients with chronic back pain: A randomized clinical trial. JAMA psychiatry.

Hilton, L., Hempel, S., Ewing, B. A., Apaydin, E., Xenakis, L., Newberry, S., ... & Maglione, M. A. (2017). Mindfulness meditation for chronic pain: systematic review and meta-analysis. Annals of Behavioral Medicine, 51(2), 199-213.

Louw, A., Puentedura, E. J., Zimney, K., & Schmidt, S. (2016). Know pain, know gain? A perspective on pain neuroscience education in physical therapy. journal of orthopaedic & sports physical therapy, 46(3), 131-134.

Lumley, M. A., & Schubiner, H. (2019). Psychological therapy for centralized pain: an integrative assessment and treatment model. Psychosomatic medicine, 81(2), 114.

Owen, P. J., Miller, C. T., Mundell, N. L., Verswijveren, S. J., Tagliaferri, S. D., Brisby, H., ... & Belavy, D. L. (2020). Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis. British journal of sports medicine, 54(21), 1279-1287.

Sheng, J., Liu, S., Wang, Y., Cui, R., & Zhang, X. (2017). The link between depression and chronic pain: neural mechanisms in the brain. Neural plasticity.

Shiri, R., Coggon, D., & Falah-Hassani, K. (2018). Exercise for the prevention of low back pain: systematic review and meta-analysis of controlled trials. American journal of epidemiology, 187(5), 1093-1101.

Zhuo, M. (2016). Neural mechanisms underlying anxiety-chronic pain interactions. Trends in neurosciences, 39(3), 136-145.