Buck interviews Dr. Dennis Hughes, a concierge physician with a special interest in lipidology. They discuss the complexities of cholesterol, the importance of understanding lipid profiles, and the role of various lipoproteins in cardiovascular health. Dr. Hughes emphasizes the need for modern medicine to move beyond outdated notions of 'good' and 'bad' cholesterol, advocating for a more nuanced understanding of lipid management. The discussion also covers key lab tests, the significance of apolipoprotein B, and the future of pharmacotherapy in lipid management. 04:51 Understanding Cholesterol: Beyond Good and Bad   08:25 Key Lab Tests for Lipid Management   11:12 The Role of Apolipoprotein B in Cardiovascular Health   14:44 The Complexities of HDL and Its Functions   19:11 The Misconceptions Around LDL and HDL Ratios   34:42 Pharmacotherapy: Statins and Beyond